Vander Heiden, Matthew G.: search on Z-Library

Fundraising September 15, 2024 – October 1, 2024 About fundraising

The world's largest scientific articles store. 70,000,000+ articles for free.

Fundraising September 15, 2024 – October 1, 2024

Z-Library is one of the largest online libraries in the world that contains over 17,000,000 books and 84,837,000 articles. We aim to make literature accessible to everyone. Today (September 15, 2024) we've started additional fundraising to project maintenance and development.

Also UNLIMITED downloads (for 31 days after the day of making donation) are available for ALL contributors who will donate during the fundraising period till October 1, 2024.

About fundraisingRead more

Make a donation

1

Metabolism in the Tumor Microenvironment

Lau, Allison N., Vander Heiden, Matthew G.

Journal:

Annual Review of Cancer Biology

Year:

2020

Language:

english

File:

PDF, 3.77 MB

english, 2020

2

Aerobic Glycolysis: Meeting the Metabolic Requirements of Cell Proliferation

Lunt, Sophia Y., Vander Heiden, Matthew G.

Journal:

Annual Review of Cell and Developmental Biology

Year:

2011

Language:

english

File:

PDF, 434 KB

english, 2011

3

Understanding the Intersections between Metabolism and Cancer Biology

Vander Heiden, Matthew G., DeBerardinis, Ralph J.

Journal:

Year:

2017

Language:

english

File:

PDF, 1.21 MB

english, 2017

4

Targeting cancer metabolism: a therapeutic window opens

Vander Heiden, Matthew G.

Journal:

Nature Reviews Drug Discovery

Year:

2011

Language:

english

File:

PDF, 847 KB

english, 2011

5

Pyruvate kinase: Function, regulation and role in cancer

Israelsen, William J., Vander Heiden, Matthew G.

Journal:

Seminars in Cell & Developmental Biology

Year:

2015

Language:

english

File:

PDF, 249 KB

english, 2015

6

Critical Functions of the Lysosome in Cancer Biology

Davidson, Shawn M., Vander Heiden, Matthew G.

Journal:

Annual Review of Pharmacology

Year:

2017

Language:

english

File:

PDF, 670 KB

english, 2017

7

The Reverse Warburg Effect: Glycolysis inhibitors prevent the tumor promoting effects of caveolin-1 deficient cancer associated fibroblasts

Bonuccelli, Gloria, Whitaker-Menezes, Diana, Castello-Cros, Remedios, Pavlides, Stephanos, Pestell, Richard G., Fatatis, Alessandro, Witkiewicz, Agnieszka K., Vander Heiden, Matthew G., Migneco, Gemma

Journal:

Year:

2010

Language:

english

File:

PDF, 2.64 MB

english, 2010

8

Activation of a Metabolic Gene Regulatory Network Downstream of mTOR Complex 1

Katrin Düvel, Jessica L. Yecies, Suchithra Menon, Pichai Raman, Alex I. Lipovsky, Amanda L. Souza, Ellen Triantafellow, Qicheng Ma, Regina Gorski, Stephen Cleaver, Matthew G. Vander Heiden, Jeffrey P.

Journal:

Year:

2010

Language:

english

File:

PDF, 2.02 MB

english, 2010

9

Heterogeneity of tumor-induced gene expression changes in the human metabolic network

Hu, Jie, Locasale, Jason W, Bielas, Jason H, O'Sullivan, Jacintha, Sheahan, Kieran, Cantley, Lewis C, Heiden, Matthew G Vander, Vitkup, Dennis

Journal:

Nature Biotechnology

Year:

2013

Language:

english

File:

PDF, 1.21 MB

english, 2013

10

Pyruvate as a Pivot Point for Oncogene-Induced Senescence

Olenchock, Benjamin A., Vander Heiden, Matthew G.

Journal:

Year:

2013

Language:

english

File:

PDF, 262 KB

english, 2013

11

Cell-State-Specific Metabolic Dependency in Hematopoiesis and Leukemogenesis

Wang, Ying-Hua, Israelsen, William J., Lee, Dongjun, Yu, Vionnie W.C., Jeanson, Nathaniel T., Clish, Clary B., Cantley, Lewis C., Vander Heiden, Matthew G., Scadden, David T.

Journal:

Year:

2014

Language:

english

File:

PDF, 3.24 MB

english, 2014

12

Supporting Aspartate Biosynthesis Is an Essential Function of Respiration in Proliferating Cells

Sullivan, Lucas B., Gui, Dan Y., Hosios, Aaron M., Bush, Lauren N., Freinkman, Elizaveta, Vander Heiden, Matthew G.

Journal:

Year:

2015

Language:

english

File:

PDF, 1.19 MB

english, 2015

13

Amino Acids Rather than Glucose Account for the Majority of Cell Mass in Proliferating Mammalian Cells

Hosios, Aaron M., Hecht, Vivian C., Danai, Laura V., Johnson, Marc O., Rathmell, Jeffrey C., Steinhauser, Matthew L., Manalis, Scott R., Vander Heiden, Matthew G.

Journal:

Developmental Cell

Year:

2016

Language:

english

File:

PDF, 1.53 MB

english, 2016

14

mTORC1 Activator SLC38A9 Is Required to Efflux Essential Amino Acids from Lysosomes and Use Protein as a Nutrient

Wyant, Gregory A., Abu-Remaileh, Monther, Wolfson, Rachel L., Chen, Walter W., Freinkman, Elizaveta, Danai, Laura V., Vander Heiden, Matthew G., Sabatini, David M.

Journal:

Year:

2017

Language:

english

File:

PDF, 4.61 MB

english, 2017

15

Evaluation of thieno[3,2-b]pyrrole[3,2-d]pyridazinones as activators of the tumor cell specific M2 isoform of pyruvate kinase

Jian-kang Jiang, Matthew B. Boxer, Matthew G. Vander Heiden, Min Shen, Amanda P. Skoumbourdis, Noel Southall, Henrike Veith, William Leister, Christopher P. Austin, Hee Won Park, James Inglese, Lewis

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2010

Language:

english

File:

PDF, 855 KB

english, 2010

16

Role of Bcl-2 family members in apoptotic cell death

Thompson, Craig B., Heiden, Matthew Vander, Chang, Brian S., Minn, Andrew J., Sattler, Michael, Liang, Heng, Muchmore, Steven W., Fesik, Stephen W.

Journal:

Kidney International

Year:

1999

Language:

english

File:

PDF, 84 KB

english, 1999

17

10.1038/70237

Vander Heiden, Matthew G., Thompson, Craig B.

Journal:

Nature Cell Biology

Year:

1999

Language:

english

File:

PDF, 503 KB

english, 1999

18

The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth

Christofk, Heather R., Vander Heiden, Matthew G., Harris, Marian H., Ramanathan, Arvind, Gerszten, Robert E., Wei, Ru, Fleming, Mark D., Schreiber, Stuart L., Cantley, Lewis C.

Journal:

Year:

2008

Language:

english

File:

PDF, 488 KB

english, 2008

19

Pyruvate kinase M2 is a phosphotyrosine-binding protein

Christofk, Heather R., Vander Heiden, Matthew G., Wu, Ning, Asara, John M., Cantley, Lewis C.

Journal:

Year:

2008

Language:

english

File:

PDF, 496 KB

english, 2008

20

Cancer's insatiable appetite

Locasale, Jason W, Cantley, Lewis C, Heiden, Matthew G Vander

Journal:

Nature Biotechnology

Year:

2009

Language:

english

File:

PDF, 154 KB

english, 2009

21

Redox regulation of p53 during hypoxia

Chandel, Navdeep S, Vander Heiden, Matthew G, Thompson, Craig B, Schumacker, Paul T

Journal:

Year:

2000

Language:

english

File:

PDF, 288 KB

english, 2000

22

Evaluation of Substituted N,N′-Diarylsulfonamides as Activators of the Tumor Cell Specific M2 Isoform of Pyruvate Kinase

Shen, Min, Skoumbourdis, Amanda P., Southall, Noel, Veith, Henrike, Leister, William, Austin, Christopher P., Park, Hee Won, Boxer, Matthew B., Jiang, Jian-kang, Vander Heiden, Matthew G.

Journal:

Journal of Medicinal Chemistry

Year:

2010

Language:

english

File:

PDF, 2.03 MB

english, 2010

23

Identification of small molecule inhibitors of pyruvate kinase M2

Matthew G. Vander Heiden, Heather R. Christofk, Eli Schuman, Alexander O. Subtelny, Hadar Sharfi, Edward E. Harlow, Jun Xian, Lewis C. Cantley

Journal:

Biochemical Pharmacology

Year:

2010

Language:

english

File:

PDF, 392 KB

english, 2010

24

2-Oxo-N-aryl-1,2,3,4-tetrahydroquinoline-6-sulfonamides as activators of the tumor cell specific M2 isoform of pyruvate kinase

Martin J. Walsh, Kyle R. Brimacombe, Henrike Veith, James M. Bougie, Thomas Daniel, William Leister, Lewis C. Cantley, William J. Israelsen, Matthew G. Vander Heiden, Min Shen, Douglas S. Auld, Craig

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2011

Language:

english

File:

PDF, 1.54 MB

english, 2011

25

ATP Consumption Promotes Cancer Metabolism

William J. Israelsen, Matthew G. Vander Heiden

Journal:

Year:

2010

Language:

english

File:

PDF, 273 KB

english, 2010

26

Metabolic Regulation of Protein N-Alpha-Acetylation by Bcl-xL Promotes Cell Survival

Caroline H. Yi, Heling Pan, Jan Seebacher, Il-Ho Jang, Sven G. Hyberts, Gregory J. Heffron, Matthew G. Vander Heiden, Renliang Yang, Fupeng Li, Jason W. Locasale, Hadar Sharfi, Bo Zhai, Ricard Rodrigu

Journal:

Year:

2011

Language:

english

File:

PDF, 1.49 MB

english, 2011

27

METabolic Adaptations in the Tumor MYCroenvironment

Shawn M. Davidson, Matthew G. Vander Heiden

Journal:

Cell Metabolism

Year:

2012

Language:

english

File:

PDF, 222 KB

english, 2012

28

Glucose Addiction of TSC Null Cells Is Caused by Failed mTORC1-Dependent Balancing of Metabolic Demand with Supply

Andrew Y. Choo, Sang Gyun Kim, Matthew G. Vander Heiden, Sarah J. Mahoney, Hieu Vu, Sang-Oh Yoon, Lewis C. Cantley, John Blenis

Journal:

Year:

2010

Language:

english

File:

PDF, 1.45 MB

english, 2010

29

Bcl-xL Regulates the Membrane Potential and Volume Homeostasis of Mitochondria

Matthew G. Vander Heiden, Navdeep S. Chandel, Edward K. Williamson, Paul T. Schumacker, Craig B. Thompson

Journal:

Year:

1997

Language:

english

File:

PDF, 469 KB

english, 1997

30

The CD28 and CTLA-4 Receptors Associate with the Serine/Threonine Phosphatase PP2A

Ellen Chuang, Timothy S. Fisher, Rodney W. Morgan, Michael D. Robbins, James M. Duerr, Matthew G. Vander Heiden, Joseph P. Gardner, John E. Hambor, Mark J. Neveu, Craig B. Thompson

Journal:

Year:

2000

Language:

english

File:

PDF, 252 KB

english, 2000

31

Bcl-xL Prevents Cell Death following Growth Factor Withdrawal by Facilitating Mitochondrial ATP/ADP Exchange

Matthew G.Vander Heiden, Navdeep S Chandel, Paul T Schumacker, Craig B Thompson

Journal:

Year:

1999

Language:

english

File:

PDF, 228 KB

english, 1999

32

PHGDH amplification and altered glucose metabolism in human melanoma

Edouard Mullarky, Katherine R. Mattaini, Matthew G. Vander Heiden, Lewis C. Cantley, Jason W. Locasale

Journal:

Pigment Cell & Melanoma Research

Year:

2011

Language:

english

File:

PDF, 1.43 MB

english, 2011

33

Amplification of phosphoglycerate dehydrogenase diverts glycolytic flux and contributes to oncogenesis

Locasale, Jason W, Grassian, Alexandra, Beroukhim, Rameen, Meyerson, Matthew, Wagner, Gerhard, Asara, John M, Brugge, Joan S, Vander Heiden, Matthew G, Cantley, Lewis C

Journal:

BMC Proceedings

Year:

2012

Language:

english

File:

PDF, 175 KB

english, 2012

34

Understanding Metabolic Regulation and Its Influence on Cell Physiology

Metallo, Christian M., Vander Heiden, Matthew G.

Journal:

Year:

2013

Language:

english

File:

PDF, 956 KB

english, 2013

35

BCAT1 defines gliomas by IDH status

Mayers, Jared R, Vander Heiden, Matthew G

Journal:

Nature Medicine

Year:

2013

Language:

english

File:

PDF, 428 KB

english, 2013

36

Reductive glutamine metabolism is a function of the α-ketoglutarate to citrate ratio in cells

Fendt, Sarah-Maria, Bell, Eric L., Keibler, Mark A., Olenchock, Benjamin A., Mayers, Jared R., Wasylenko, Thomas M., Vokes, Natalie I., Guarente, Leonard, Heiden, Matthew G. Vander, Stephanopoulos, Gr

Journal:

Nature Communications

Year:

2013

Language:

english

File:

PDF, 674 KB

english, 2013

37

Metabolic targets for cancer therapy

Galluzzi, Lorenzo, Kepp, Oliver, Heiden, Matthew G. Vander, Kroemer, Guido

Journal:

Nature Reviews Drug Discovery

Year:

2013

Language:

english

File:

PDF, 785 KB

english, 2013

38

Metabolic targets for cancer therapy

Galluzzi, Lorenzo, Kepp, Oliver, Heiden, Matthew G. Vander, Kroemer, Guido

Journal:

Nature Reviews Drug Discovery

Year:

2013

Language:

english

File:

PDF, 45 KB

english, 2013

39

Tracing Compartmentalized NADPH Metabolism in the Cytosol and Mitochondria of Mammalian Cells

Lewis, Caroline A., Parker, Seth J., Fiske, Brian P., McCloskey, Douglas, Gui, Dan Y., Green, Courtney R., Vokes, Natalie I., Feist, Adam M., Vander Heiden, Matthew G., Metallo, Christian M.

Journal:

Year:

2014

Language:

english

File:

PDF, 1.28 MB

english, 2014

40

Human Phosphoglycerate Dehydrogenase Produces the Oncometabolite d -2-Hydroxyglutarate

Fan, Jing, Teng, Xin, Liu, Ling, Mattaini, Katherine R., Looper, Ryan E., Vander Heiden, Matthew G., Rabinowitz, Joshua D.

Journal:

ACS Chemical Biology

Year:

2015

Language:

english

File:

PDF, 1.98 MB

english, 2015

41

Seeing the Warburg effect in the developing retina

Fiske, Brian P., Vander Heiden, Matthew G.

Journal:

Nature Cell Biology

Year:

2012

Language:

english

File:

PDF, 152 KB

english, 2012

42

Famine versus feast: understanding the metabolism of tumors in vivo

Mayers, Jared R., Vander Heiden, Matthew G.

Journal:

Trends in Biochemical Sciences

Year:

2015

Language:

english

File:

PDF, 750 KB

english, 2015

43

Understanding the complex-I-ty of metformin action: limiting mitochondrial respiration to improve cancer therapy

Luengo, Alba, Sullivan, Lucas B, Heiden, Matthew G Vander

Journal:

Year:

2014

Language:

english

File:

PDF, 819 KB

english, 2014

44

Rewiring of glycolysis in cancer cell metabolism

Locasale, Jason W., Vander Heiden, Matthew G., Cantley, Lewis C.

Journal:

Year:

2010

Language:

english

File:

PDF, 106 KB

english, 2010

45

Acetate metabolism in cancer cells

Hosios, Aaron M, Vander Heiden, Matthew G

Journal:

Cancer & Metabolism

Year:

2014

Language:

english

File:

PDF, 177 KB

english, 2014

46

Antibody-Mediated Neutralization of Perfringolysin O for Intracellular Protein Delivery

Yang, Nicole J., Liu, David V., Sklaviadis, Demetra, Gui, Dan Y., Vander Heiden, Matthew G., Wittrup, K. Dane

Journal:

Molecular Pharmaceutics

Year:

2015

Language:

english

File:

PDF, 892 KB

english, 2015

47

An epitope tag alters phosphoglycerate dehydrogenase structure and impairs ability to support cell proliferation

Mattaini, Katherine R, Brignole, Edward J, Kini, Mitali, Davidson, Shawn M, Fiske, Brian P, Drennan, Catherine L, Vander Heiden, Matthew G

Journal:

Cancer & Metabolism

Year:

2015

Language:

english

File:

PDF, 3.14 MB

english, 2015

48

Glutamine Synthetase Is a Genetic Determinant of Cell Type–Specific Glutamine Independence in Breast Epithelia

Kung, Hsiu-Ni, Marks, Jeffrey R., Chi, Jen-Tsan, Vander Heiden, Matthew G.

Journal:

Year:

2011

Language:

english

File:

PDF, 1.76 MB

english, 2011

49

Overlapping Yet Distinct Promoter Activities of Two Arabidopsis Genes Coding for Nearly Identical Isoforms of the Acyl Carrier Protein

Scott R. Baerson, Matthew G. Vander Heiden and Gayle K. Lamppa

Journal:

International Journal of Plant Sciences

Year:

1998

Language:

english

File:

PDF, 1.39 MB

english, 1998

50

Stopping the Clock with MYC

Lau, Allison N., Vander Heiden, Matthew G.

Journal:

Year:

2015

Language:

english

File:

PDF, 277 KB

english, 2015